Medizinische Klinik und Poliklinik II

Direktor: Prof. Dr. H. Einsele
Zentrum Innere Medizin
Oberdürrbacher Straße  6
D-97080  Würzburg

Institute presentation

The University of Würzburg (Universitätsklinikum Würzburg, UKW) is a major academic teaching hospital located in the north of the state of Bavaria, right in the center of Germany. The UKW combines excellency in patient-care, dedication in teaching and education of physicians and scientists as well as top-notch basic and translational research.

The University of Würzburg has a more than 400-year history of academic culture - among the most prominent scientists who worked and teached in Würzburg are Wilhelm Conrad Röntgen, discoverer of the X-rays, and Rudolf Virchow, the world-renowned pathologist who coined the term "Leukemia".

The Department of Medicine II, led by Professor Hermann Einsele, provides in-patient services and out-patient clinics in Hematology and Oncology, and also Gastroenterology, Hepatology, Rheumatology, Psychosomatics and Infectious Diseases. A cornerstone in Hematology is the Bone Marrow Transplantation Program which was established in 2005 and has since become the second largest program in Germany, and one of the leading programs in the field.

The Hematopoietic Stem Cell Transplantation Program at the UKW has experience in allogeneic, haploidentical and cord blood transplantation. It plays an active role in national and international clinical trial networks, and has a track record for developing novel and innovative treatment strategies to augment the clinical benefit of patients undergoing this procedure, reducing toxicity and undesired side-effects such as Graft-versus-Host Disease and infections, with a particular focus on the use of antibody- and cell-based immunotherapy.  

The scientists are concentrated on translational research on adoptive cell therapy for hematological malignancies and have been the first in Europe to use cellular therapy for treatment of infections. They also pioneered the use of bi-specific antibodies for redirecting T cells for the control of lymphoproliferative disorders. They have specific expertise in cell selection and transfer, DC vaccination, redirection of t cells, cell expansion and NSG mice as well as in vivo Bioimaging.

The UKW Department of Medicine II was part of the 'Allostem' project in the 6th EU Framework Program, coordinated the EU FP6 project 'Manasp', and participates in the two EU FP7 consortia 'Nano' and 'Optatio'. It is now the project coordinator and leading institution in the 7th EU Framework Program 'T Control'.

The University of Würzburg Medical Center (UKW)
The University of Würzburg Medical Center (UKW)

Coordinator / Lead Investigator

Hermann Einsele

Prof. Dr. Hermann Einsele

Phone: +49 (0)931 20140001


Dr. Götz Ulrich Grigoleit

Assistant Professor / Clinician Scientist

Phone: + 49 (0)931 201 40942


Dr. Michael Hudecek

Clinical and Research Fellow / Clinician Scientist

Phone: + 49 (0)931 201 71091


Dr. Sophia Danhof

Clinical and Research Fellow / Clinician Scientist

Phone: + 49 (0)931 201 44922


Prof. Dr. Stephan Mielke

Professor of Medicine

Phone: + 49 (0)931 201 44945